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Additionally, metabolic abnormalities, including lipid deposition in articular cartilage, have been linked to OA risk, highlighting the importance of lipidomic profiles in predicting obesity-associated OA [153]

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Most patients experience improvement as physiological adaptation occurs, usually within 2-3 weeks of dose stabilization

10.1002/jnr.21158 29 KohJ

El objetivo principal fue evaluar la efectividad y la seguridad en la reduccin de peso y HbA1c en pacientes con diabetes mellitus tipo 2 con mltiples tratamientos de base ms la combinacin de dapagliflozina, durante al menos 12 meses, y AGLP1