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Recreational doses are generally much larger than prescribed therapeutic doses and carry a far greater risk of serious side effects

10.2337/dc12-2006 [DOI] [PMC free article] [PubMed] [Google Scholar] Ahrn B., Masmiquel L., Kumar H., Sargin M., Karsbl J

Van Krieken JH, Boom BW, Scheffer E

We see a lot of patients that are very frustrated by that, who feel stuck, says Lauren Newman, a registered dietitian and certified eating disorders specialist who focuses on disordered eating and diabetes care

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Adverse effects: Orlistat-associated to liver failure Orlistat, a drug inhibiting pancreatic lipase and aimed at aiding weight loss, has been linked to severe liver-related side effects, including the formation of gallstones, liver inflammation with bile obstruction, and acute liver failure, as highlighted in various studies [5, 42, 66,67,68,69]