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Another study found that eating a whole avocado with a meal increased GLP-1 levels while also reducing insulin levels

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This pathway directly targets the increase of basal energy expenditure and promotes hepatic lipid oxidation (fat burning in the liver)

Patients already managing nausea on one medication face compounded risk by introducing a second peptide agonist, potentially leading to dehydration, electrolyte imbalance, and reduced medication adherence

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Because of these reasons, individuals with severe diabetes complications are often advised to avoid alcohol while on tirzepatide