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p73 Polyclonal Antibody, 20ul[BT-AP06862] Antibody Development CD1C encodes a member of

SKU: 7963987460

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p73 Polyclonal Antibody, 20ul[BT-AP06862] Antibody Development CD1C encodes a member ofTP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many

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Description

CD1C encodes a member of the CD1 family of transmembrane glycoproteins

Decreased concentrations of CER has been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome

The protein functions as a steroid-hormone activated transcription factor

It is specifically expressed in hematopoietic cells

Overexpression of CAGE leads to the activation of FAK

p73 Polyclonal Antibody, 20ul[BT-AP06862] Antibody Development CD1C encodes a member ofTP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many

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