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Nutr Cancer 1994

In male rat AD models, ICV administration of A 25-35 combined with IGF-1 protects the hippocampal somatostatin system from A-induced damage

While some people notice a decreased appetite and weight loss in the first four weeks of treatment, it can take several months for them to reach their goals

Adipose tissue produces estrogen through aromatization of androgens, and substantial fat loss reduces this endogenous estrogen production, potentially affecting bone density, particularly in postmenopausal women