BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos Expression studies in yeast and

Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35

Multiple alternatively spliced transcript variants encoding the same protein are observed

Alternate splicing of this gene generates several transcript variants encoding different isoforms

this protein is sometimes secreted

Volume Range: The MicroPette Plus offers a volume range of 0

BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos Expression studies in yeast andBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated) combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal