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In a population of individuals experienced with drugs of abuse, a single dose of 400 mg of bupropion produced mild amphetamine-like activity as compared with placebo on the Morphine-Benzedrine Subscale of the Addiction Research Center Inventories (ARCI) and a score intermediate between placebo and amphetamine on the Liking Scale of the ARCI

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A total of 697 KOs were significantly less abundant in all the treatments compared to T1, and the biosynthesis of acids and sugars were the main down-represented high-hierarchy functions due to AcM administration (Fig

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