MDC1(Phospho Ser513) Polyclonal Antibody, 50ul DNA Libraries Synthesis H3 Lys-9 trimethylation is also

H3 Lys-9 trimethylation is also required to direct DNA methylation at pericentric repeats

LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin

MIM 603478)

may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes

Expression is highest in the cortex

MDC1(Phospho Ser513) Polyclonal Antibody, 50ul DNA Libraries Synthesis H3 Lys-9 trimethylation is alsoThe protein encoded by this gene contains an N terminal forkhead domain, two BRCA1 C terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41 amino acid sequence. The encoded protein is required to activate the intra S phase and G2 M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double strand breaks through its BRCT motifs, and