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The methods for overcoming this feedback mechanism included the use of bispecific antibodies and other small molecule tyrosine kinase inhibitors (TKIs)

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Additional effect of dietary Fiber in patients with type 2 diabetes mellitus using metformin and sulfonylurea: An open-label, pilot trial

SIRT1, an NAD + -dependent class III histone deacetylase, regulates hepatic lipid metabolism through deacetylation of multiple transcription factors and metabolic enzymes, exerting a bidirectional effect on lipid homeostasis by inhibiting fat synthesis and promoting fatty acid oxidation