Raf-1 Polyclonal Antibody, 100ul[BT-AP13534] Diagnostic Probes & Oligos resulting in the creation of

resulting in the creation of an N-terminal chain and the corresponding C-terminal chain

Ideal for cell culture

The product of this gene functions in the nucleotide excision repair pathway

Multiple transcript variants encoding different isoforms have been identified

alpha-type (AC Q9Y4C0) and beta-type (shown here)

Raf-1 Polyclonal Antibody, 100ul[BT-AP13534] Diagnostic Probes & Oligos resulting in the creation ofThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.