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This matters for this comparison because Ros published Ro Body Program materials reference 15% average body weight reduction at week 68 a figure from the STEP clinical trial program, which studied branded Wegovy, not compounded semaglutide

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The group receiving the highest retatrutide dose of 12mg/weekly experienced a significant 24.2% reduction in weight, compared to a modest 2.1% reduction in the placebo group [21]

Endocannabinoid signaling is known to be disrupted by chronic exposure to alcohol or cannabinoid drugs