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MCLN2 Rabbit Polyclonal Antibody, 100ul Enzyme-Linked Immunosorbent Assay (ELISA) ARID1B (AT-rich interaction domain 1B)

SKU: 88594024249

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MCLN2 Rabbit Polyclonal Antibody, 100ul Enzyme-Linked Immunosorbent Assay (ELISA) ARID1B (AT-rich interaction domain 1B)Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals the mucolipin family includes 3 members MCOLN1 (MIM 605248) MCOLN2 and MCOLN3 (MIM 607400) that exhibit a common 6 membrane spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al. 2007

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Description

ARID1B (AT-rich interaction domain 1B) encodes an AT-rich DNA interacting domain-containing protein

Among its related pathways are Regulation of autophagy and Cellular Senescence

This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with

DNTT is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers

This encoded protein may play a role in hematopoiesis

MCLN2 Rabbit Polyclonal Antibody, 100ul Enzyme-Linked Immunosorbent Assay (ELISA) ARID1B (AT-rich interaction domain 1B)Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals the mucolipin family includes 3 members MCOLN1 (MIM 605248) MCOLN2 and MCOLN3 (MIM 607400) that exhibit a common 6 membrane spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al. 2007

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