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A., Richardson, G

Reported Benefits: Weight Loss Neuroprotective Improved Fertility Treatment of PCOS Smoking Cessation Cardiovascular Benefits Possible side effects and contraindications: The most common side effects seen with Semaglutide during the clinical trials included gastrointestinal events commonly seen with this agent class and included nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, dyspepsia, dizziness, abdominal distension, eructation, hypoglycemia in patients with type 2 diabetes, flatulence, gastroenteritis, and gastroesophageal reflux disease

I tell them that they are not FDA cleared (except the obvious ones like insulin, the GLP-1s, etc.)

Critical Care medicine

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Zepbound carries an FDA boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)