HEXA Polyclonal Antibody, 50ul Cell Culture Dishes induction:Down-regulated in multiple tumors

induction:Down-regulated in multiple tumors

A pseudogene of AURKB is located on chromosome 8

The protein encoded by this gene is a major structural protein of the bone matrix

This gene encodes a member of the four-and-a-half-LIM-only protein family

Functional studies in mice determined that this protein plays a role in vestibular morphogenesis

HEXA Polyclonal Antibody, 50ul Cell Culture Dishes induction:Down-regulated in multiple tumorsHEXA encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons,