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Flavonoids as GLP-1R Agonists Several flavonoids have been shown to enhance GLP-1 secretion in intestinal cell models and tissues, leading to increased plasma GLP-1 concentrations in animal studies

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Their dehydroxylation by bacteria in the intestine produces deoxycholic acid (3,12 dihydroxy) and lithocholic acid (3 monohydroxy), known as secondary bile acids

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Research Context BPC-157 (Body Protection Compound 157) is a synthetic pentadecapeptide corresponding to a 15-amino-acid partial sequence (residues 14 to 28) of a larger gastroprotective protein identified in human gastric juice