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GSK said the PDE3/4 inhibitor will support its efforts to "treat patients across the widest spectrum of COPD by including those who face continued dyspnoea (shortness of breath) or who are unlikely to receive inhaled corticosteroids or biologics, based on their disease profile." The drug also looks likely to be compatible with GSK's dry powder inhaler (DPI) technology

Bupropion can cause side effects like dry mouth, insomnia, and headaches

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However, persistent abnormal angiogenesis is a hallmark of cancer, promoting tumor growth and metastasis (110)