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FoxO3A(Phospho Ser253) Polyclonal Antibody, 50ul Liquid Handling &Storage It is located in the

SKU: 92582559045

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FoxO3A(Phospho Ser253) Polyclonal Antibody, 50ul Liquid Handling &Storage It is located in theThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

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Description

It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS

It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas

The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage

The encoded protein has been shown to control the cellular level of FBXL7| a protein that induces mitotic arrest| by targeting it for polyubiquitylation and proteasomal degradation

This gene encodes an enzyme belonging to the protein tyrosine kinase family| and it plays a role in T-cell development and lymphocyte activation

FoxO3A(Phospho Ser253) Polyclonal Antibody, 50ul Liquid Handling &Storage It is located in theThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

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