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Additionally, certain variants in genes related to antioxidant response, such as the catalase (CAT) gene and the glutathione peroxidase (GPX) gene, have been associated with increased susceptibility to vitiligo.67,69,70 Furthermore, vitiligo has been associated with defective recycling of tetrahydrobiopterin (6BH4), essential for melanin formation, leading to an excess of 7BH4 and inhibition of phenylalanine hydroxylase (PAH)

In the rats that received GHK-Cu, the researchers found an increase in total protein and collagen synthesis greater than that of the placebo group, demonstrating that GHK-Cu is able to increase extracellular matrix accumulation in wounds in vivo .28 Are GHK-Cu copper peptides safe

It belongs in a peptide therapy guide where research status, sourcing, compounding quality, dosing, and clinician oversight all need extra scrutiny

Either way, the message gets delivered just with some difference in timing

However, increasing evidence points towards other sites of action that might also have an important role, including the gastrointestinal tract, the gut microbial communities and the tissue-resident immune cells