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10.1126/scitranslmed.adp2564 169 RuanY.LuoH.TangJ.JiM.YuD.YuQ.et al (2024)

As AD is characterized by iron accumulation in brain cells, exacerbating oxidative damage and cognitive decline (96100), these inhibitors show therapeutic promise

However, combination therapies require careful medical supervision to monitor for interactions and optimize timing

doi: 10.3390/molecules25122806 131

M.NawazM

Intervention studies have shown that supplementation with riboflavin (the MTHFR cofactor) effectively lowers blood pressure, specifically in individuals with the variant MTHFR 677TT genotype

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