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Often called the master antioxidant, it protects cells from oxidative stress, neutralizes harmful free radicals, and supports the bodys natural detoxification processes

51,124 Additionally, endothelial dysfunction associated with elevated serum uric acid levels leads to a low-grade inflammatory state and vascular activation of the angiotensin system

This oxidative stress directly damages mitochondrial DNA and the delicate lipid membranes of the organelles

Two different microglial phenotypes have also been described in SOD1 G93A transgenic mice

Nevertheless, the findings in adult immune cells suggest an immunoregulating role for glutamate, with effects that are highly dependent on the context and the concentration

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