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Precautions and not-recommended situations include history of pancreatitis, severe gastroparesis or other serious gastrointestinal disease, pregnancy/lactation (discontinue before conception), and type 1 diabetes

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(1997) J Mol Biol 274 : 84-100 PubMed: 9398518 Search on PubMed DOI: Primary Citation Related Structures: 10GS, 5GSS, 6GSS, 7GSS, 8GSS, 9GSS PubMed Abstract: The human pi-class glutathione S-transferase (hGST P1-1) is a target for structure-based inhibitor design with the aim of developing drugs that could be used as adjuvants in chemotherapeutic treatment

Excessive ROS levels can induce transcription factors like nuclear factor-kappa B (NF-kB), which is accountable for regulating cell growth and oncogenesis [37, 39]

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It has been suggested that culture under reduced oxygen tension is critical for maintaining physiological embryo development and increasing reproductive competence