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Abbreviations ATF3: Activating transcription factor 3 BiP: Endoplasmic reticulum chaperone BiP ER: Endoplasmic reticulum GLP-1: Glucagon-like peptide 1 GLP-1R: Glucagon-like peptide 1 receptor HPF: Hydroxyphenyl fluorescein iPSC: Induced pluripotent stem cell JunB: Transcription factor JunB KIRRE2: Kin of IRRE-like protein 2 KO: Knockout NPC: Neural precursor cell OCR: Oxygen consumption rate OCT4: Octamer binding protein 4 siCT: Control siRNA WFS1: Wolframin WT: Wild-type ZIC1: Zinc finger protein ZIC 1 References Fraser FC, Gunn T (1977) Diabetes mellitus, diabetes insipidus, and optic atrophy

For example, certain intestinal bacteria can synthesize 5-hydroxytryptamine (5-HT), and its levels are closely linked to the severity of depressive symptoms [489, 490]

Beetroot leaves were historically consumed before the roots ever were, even though today many people prefer to consume the sweet roots and discard the more bitter but very beneficial greens and stems

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