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Last week, the TGA issued an alert over use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 RAs) before procedures involving general anaesthesia or deep sedation

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A clinical review published in the International Journal of Molecular Sciences documenting the pharmacological basis and clinical applications of therapeutic peptides, confirming their classification as off-label compounded preparations outside FDA-approved indications provides the regulatory context