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Elevated levels of ROS destroys the physiological functions by cross-linking with lipids, protein, and DNA, which lead to several diseases, including cancer, cardiovascular, diabetes, arthritis, neurological disorders and others metabolic diseases

Plant Cell 25:34913505 Qin F, Shinozaki K, Yamaguchi-Shinozaki K (2011) Achievements and challenges in understanding plant abiotic stress responses and tolerance

MUC1 and HIF-1alpha signaling crosstalk induces anabolic glucose metabolism to impart gemcitabine resistance to pancreatic cancer

Although the physiological role of ferroptosis remains unclear, it can be triggered by pharmacological disruption of cellular lipid peroxidation repair or by oxidative stress associated with degeneration

This protocol evaluates binding free energy changes by accounting for backbone flexibility during mutations

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