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PKR(Phospho Thr258) Polyclonal Antibody, 50ul Cell fragmentation and collection Dual Rotary Knobs: The DLAB

SKU: 16733840037

4.8
USD162.00 USD187.00

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PKR(Phospho Thr258) Polyclonal Antibody, 50ul Cell fragmentation and collection Dual Rotary Knobs: The DLABThe protein encoded by this gene is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

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Description

Dual Rotary Knobs: The DLAB pipette features dual rotary knobs that enable all functions to be performed seamlessly

Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids

Acting as a GTPase activating protein (GAP)

Belongs to the tubulin family

IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al

PKR(Phospho Thr258) Polyclonal Antibody, 50ul Cell fragmentation and collection Dual Rotary Knobs: The DLABThe protein encoded by this gene is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

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