Sources: Tirzepatide Once Weekly for the Treatment of Obesity | New England Journal of Medicine Realworld use and effectiveness of tirzepatide among individuals without type 2 diabetes: Results from the Optum Market Clarity database PMC Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity | Obesity | JAMA Internal Medicine | JAMA Network Semaglutide StatPearls NCBI Bookshelf Safety of Semaglutide PMC Semaglutide, a glucagon like peptide-1 receptor agonist with cardiovascular benefits for management of type 2 diabetes PMC Realworld evidence on the utilization, clinical and comparative effectiveness, and adverse effects of newer GLP1RAbased weightloss therapies PMC Liraglutide for weight management: a critical review of the evidence PMC Liraglutide and not lifestyle intervention reduces soluble CD163 after comparable weight loss in obese participants with prediabetes or type 2 diabetes mellitus PMC Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial | Clinical Pharmacy and Pharmacology | JAMA | JAMA Network

Mechanism: Most are pure GLP-1 receptor agonists, but tirzepatide is unique in targeting both GLP-1 and GIP receptors
This advice applies whether youre taking a GLP-1 or not
Its dual receptor agonism targets multiple pathways involved in glucose regulation, leading to better management of diabetes
Sergey Terushkin, MD, FACS, FASMBS leads Florida Surgery & Weight Loss, one of South Floridas top clinics for medical and surgical weight loss
Prior to joining the County Attorney's Office, Armando was a federal prosecutor in Miami for over five years, which culminated in his service as the Deputy Chief of the Collateral Litigation Section