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GSC2 Polyclonal Antibody, 100ul Immunoassays The product of this gene

SKU: 2444395216

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GSC2 Polyclonal Antibody, 100ul Immunoassays The product of this geneGoosecoidlike (GSCL), a homeodomain containing gene, resides in the critical region for VCFS DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS DGS

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Description

The product of this gene catalyzes sulfonation by transferring a sulfate group to the 3' position of galactose in N-acetyllactosamine in both type 2 (Gal-beta-1-4GlcNAc-R) oligosaccharides and core-2-branched O-glycans| but not on type 1 or core-1-branched structures

|tissue specificity:Highest level in lung and spleen

ANX4 encodes a protein that has possible interactions with ATP

and may regulate cyclosporine A-mediated immunosuppression

and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells

GSC2 Polyclonal Antibody, 100ul Immunoassays The product of this geneGoosecoidlike (GSCL), a homeodomain containing gene, resides in the critical region for VCFS DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS DGS

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