EFS Rabbit Polyclonal Antibody, 100ul Gene Editing The nucleolar transcription factor 1

The nucleolar transcription factor 1 plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex

Belongs to the short-chain dehydrogenases/reductases (SDR) family

This protein interacts with and regulates signalling by NEDD9/CAS-L (neural precursor cell expressed| developmentally down-regulated 9)

endonexin II

It activates the urokinase-type plasminogen activator

EFS Rabbit Polyclonal Antibody, 100ul Gene Editing The nucleolar transcription factor 1The longest protein isoform encoded by this gene contains an SH3 domain which is known to be important in intracellular signal transduction. The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein tyrosine kinases. The function of this gene is unknown. Three alternatively spliced variants encoding different isoforms have been described for this gene.