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While Reddit, TikTok and X users have raved about their results, medical providers are more skeptical due to a lack of safety data and a lack of oversight into its murky supply chain

Rarely, allergic reactions like itching or rash can occur, and excessive or prolonged use may strain the kidneys or liver, especially in those with pre-existing conditions

To understand the comparison, you have to look at their structural origins and their incretin receptor affinities

Triple GLP-1R/GIPR/GCGR agonism retatrutide (weekly)

Diabet Med 29: e205210

10.1371/journal.pone.0004345 6 AuwerxJ.IsacssonO.SderlundJ.BalzariniJ.JohanssonM.LundbergM