CD55 Polyclonal Antibody, 100ul[BT-AP02035] ADME Chromobox protein homolog 5 is

Chromobox protein homolog 5 is enriched in the heterochromatin and associated with centromeres

This gene encodes a member of the family of secreted protein kinases

It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors

An isoform lacking exon 6 has been shown to play a role in the cohesion of centrioles (PMID: 16582621 and PMID: 18331714)

This gene encodes a protein which contains a FYVE zinc finger binding domain

CD55 Polyclonal Antibody, 100ul[BT-AP02035] ADME Chromobox protein homolog 5 isCNOT2 encodes a subunit of the multi component CCR4 NOT complex. The CCR4 NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for CNOT2.