FAK Polyclonal Antibody, 20ul[BT-AP03137] Diagnostic Probes & Oligos DUSPs are characterized by their

DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues

It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT

It was also found to be an essential component of a non-snRNA spliceosome

Mutations in this gene are a cause of type 2E pseudohypoaldosteronism

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FAK Polyclonal Antibody, 20ul[BT-AP03137] Diagnostic Probes & Oligos DUSPs are characterized by theirPTK2 encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. Focal adhesion kinase 1 is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal