ORCTL2 Polyclonal Antibody, 100ul Culture Plate Inserts The product of this gene

The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells

N-terminal

was shown to promote the survival and differentiation of dopaminergic neurons in culture

many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF

colon cancer and acute leukemia

ORCTL2 Polyclonal Antibody, 100ul Culture Plate Inserts The product of this geneSLC22A18 is one of several tumor suppressing subtransferable fragments located in the imprinted gene domain of 11p15. , an important tumor suppressor gene region. Alterations in this region have been associated with the Beckwith Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. SLC22A18 is imprinted, with preferential expression from the maternal allele. Mutations in SLC22A18 have been