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An alcohol mediated increased production of pro-oxidants, as well as adecrease in the antioxidant defense systems (enzymatic and non-enzymatic) in the liver may contribute to the development of ALD

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Clinical Microbiology Reviews , 15 (2), 194-222

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Other identified key-classifiers were glutamate, ketone bodies, and markers of glial activation, all of which emphasize the importance of mitochondrial function, oxidative stress, and metabolic waste pathways in association with HAND onset (Cassol et al

Focal adhesion kinase phosphorylation and paxillin recruitment are biologically plausible readouts for migration-related processes, but they should not be automatically treated as proof of increased proliferation