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Gastric neuroendocrine neoplasms and proton pump inhibitors: fact or coincidence

Altogether, the observed upregulation of lipid peroxidation signaling and increased levels of lipid peroxides, coupled with elevated labile iron pool (LIP) due to impaired iron homeostasis, and the reduction in antioxidants resulting from diminished expression and activity of glutathione peroxidase-4 (GPX4), collectively establish the occurrence of myocardial ferroptosis in humans with diabetic heart failure (Fig

Wang K, Ning X, Qin C, Wang J, Yan W, Zhou X

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Inhibitors of mitochondrial respiration, iron (II), and hydroxyl radical evoke release and extracellular hydrolysis of glutathione in rat striatum and substantia nigra: potential implications to Parkinson's disease

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