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ii) Utilizing the steric hindrance conferred by dimerization reduces protease access to the active site and significantly improving stability against proteases 49,50

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Consequently, the continuous excavation of genes upstream and downstream of glutamine metabolism, which can influence cancer cell invasion and metastasis-related genes, will be a promising means to contribute to the design of clinically specific relevant inhibitors

Fifth, the authors of the MOXI trial state that AOX therapy was given for at least 3 months and up to 6 months

Glutamic acid decarboxylase (GAD) catalyzes the decarboxylation of glutamic acid to form GABA