NTCP2 Rabbit Polyclonal Antibody, 20ul Serological Pipets and the protein encoded by

and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction

Defects in this gene are frequently found in patients with prostate tumors

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brain and liver

The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor

NTCP2 Rabbit Polyclonal Antibody, 20ul Serological Pipets and the protein encoded byThis gene encodes a sodium bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines