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As a functional integrative medicine practitioner, you know all about homocysteine, and how this non-essential amino acid is connected to methylation and a common genetic mutation of the MTHFR SNP

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Pro-inflammatory cytokines activate chondrocytes to release catabolic factors, which impede the production of COL2, proteoglycans, and other synthetic metabolic components, hence facilitating chondrocyte catabolic processes and the degradation of articular cartilage [39,40]

Incorporating stress-reduction techniques supports overall nutritional status

Many mechanisms, such as the regulation of lipid and glucose metabolism and insulin production, account for the beneficial effects of phytochemicals, NF-kB signalling pathway stimulation, inhibition of gluconeogenic enzymes and ROS, and activating cells [181]

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