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Ayers, Physiology, Stress Reaction

Abstract Modern lifestyles have altered diet and metabolic homeostasis, with increased sugar intake, glycemic index, and prediabetes

Activation of some enzymes in the cytochrome P-450 system such as CYP2E1 also lead to oxidative stress

Additionally, in Shank3/ mice, the expression levels of glutamate receptors are reduced in the striatum and thalamus, although no changes in the cell surface expression of GABAA receptor 1 subunits were observed in the cortex, striatum, thalamus, or cerebellum (93)