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Indeed, the components of this system are involved in the bi-directional transport of acyl moieties from cytosol to mitochondria and vice versa, thus playing a fundamental role in tuning the switch between the glucose and fatty acid metabolism

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Cysteine is mainly derived from the trans-sulfuration pathway of methionine and the reduction of cysteine [21]

Research in naturally aged mice demonstrates measurable improvements in physical performance, with treated animals showing increased running endurance and improved overall fitness metrics compared to untreated aged controls

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In vitro studies demonstrated that hepatocytes challenged with several kinds of saturated fatty acids or lysophosphatidylcholine (LPC) showed activation of the apoptotic UPR and subsequent cell death [55, 56] (Fig