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NSE2 Polyclonal Antibody, 50ul[BT-AP12036] Isothermal Amplification Diseases associated with MAP3K9 include

SKU: 20003660936

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NSE2 Polyclonal Antibody, 50ul[BT-AP12036] Isothermal Amplification Diseases associated with MAP3K9 includeE3 SUMO protein ligase component of the SMC5 SMC6 complex, a complex involved in DNA double strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1 SMC3 cohesin complex to double strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein ligase activity is required for

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Description

Diseases associated with MAP3K9 include retroperitoneal neuroblastoma

playing a role in T-cell and B-cell development and activation

The protein encoded by this gene is specifically expressed in the inner ear| and is located at the interface between the apical surface of the inner ear sensory epithelia and their overlying acellular gels

Secreted phosphoprotein 1 encoded by SPP1 is involved in the attachment of osteoclasts to the mineralized bone matrix

Data suggest that the similar protein in mouse plays an important role in trabeculation of the embryonic heart

NSE2 Polyclonal Antibody, 50ul[BT-AP12036] Isothermal Amplification Diseases associated with MAP3K9 includeE3 SUMO protein ligase component of the SMC5 SMC6 complex, a complex involved in DNA double strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1 SMC3 cohesin complex to double strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein ligase activity is required for

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