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RARBeta Polyclonal Antibody, 50ul Miscellaneous When exogenously expressed

SKU: 21832393677

4.9
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RARBeta Polyclonal Antibody, 50ul Miscellaneous When exogenously expressedRARB encodes retinoic acid receptor beta, a member of the thyroid steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating

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Description

When exogenously expressed

The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions

which inhibit adenylate cyclase activity in a dose-dependent

A pseudogene has been identified on chromosome Y

Mutations in this gene cause deafness

RARBeta Polyclonal Antibody, 50ul Miscellaneous When exogenously expressedRARB encodes retinoic acid receptor beta, a member of the thyroid steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating

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