PARP-1 (Acetyl-K521) Polyclonal Antibody, 20ul Recombinant Ab Production the gene encoding VWA5A maps

the gene encoding VWA5A maps to human chromosome 11q24

with the last serine residue replaced by alanine

Mutations in this gene are associated with Mitchell-Riley syndrome| which is characterized by neonatal diabetes with pancreatic hypoplasia| duodenal and jejunal atresia| and gall bladder agenesis

MIM 165390)

frequently in association with type I collagen

PARP-1 (Acetyl-K521) Polyclonal Antibody, 20ul Recombinant Ab Production the gene encoding VWA5A mapsThis gene encodes a chromatin associated enzyme, poly(ADP ribosyl)transferase, which modifies various nuclear proteins by poly(ADP ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be