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Lancet 1978

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Be sure to monitor your caloric intake (in writing or using a tracking app) for a few days to ensure you arent under-eating to a dangerous degree

It was demonstrated, that metabolic disturbances in hypothalamic astrocytes, caused either by selective knock-out of insulin receptors or decreased generation of reactive oxygen species (ROS) modulated glucose transport via BBB and also led to modification in behavioral responses in experimental animals [95, 96]