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doi: 10.3389/fcell.2020.00005 Received 20 September 2019 Accepted 08 January 2020 Published 24 January 2020 Volume 8 - 2020 Edited by Simone Pacini, University of Pisa, Italy Reviewed by Yhong Hee Shim, Konkuk University, South Korea

The American College of Obstetricians and Gynecologists (ACOG) has stated that compounded bioidentical hormones carry the same risks as conventional hormone therapy and lack the standardized dosing and safety data of FDA-approved alternatives [11]