TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 20ul Cell Dissociation The receptor functions as a

The receptor functions as a neurotransmitter-gated ion channel

It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner

this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas

Phosphorylation promotes association of TFEB with 14-3-3 family proteins and retention in the cytosol

Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules

TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 20ul Cell Dissociation The receptor functions as aCatalytic activity: ATP dependent breakage passage and rejoining of double stranded DNA. enzyme regulation: Specifically inhibited by the intercalating agent amsacrine. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double strand breaks. miscellaneous: Eukaryotic topoisomerase I and II can relax both negative and positive supercoils whereas prokaryotic enzymes relax only