PRMT6 Monoclonal Antibody, 100ul[BT-MCA1066] PCR Series This gene is expressed mainly

This gene is expressed mainly in testis with weak expression in the brain

Mutations in this gene cause nephronophthisis (NPHP)| an autosomal recessive kidney disease characterized by tubular basement membrane disruption| interstitial lymphohistiocytic cell infiltration| and development of cysts at the corticomedullary border of the kidneys

This gene is clustered with another family member

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of the Lutheran blood group

PRMT6 Monoclonal Antibody, 100ul[BT-MCA1066] PCR Series This gene is expressed mainlyThe protein encoded by this gene belongs to the arginine N methyltransferase family, which catalyze the sequential transfer of methyl group from S adenosyl L methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S adenosyl L homocysteine. This protein can catalyze both, the formation of omega N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the