Rb Polyclonal Antibody, 100ul[BT-AP07688] Pathway and Network Analysis It is used as a

It is used as a marker to distinguish astrocytes from other glial cells during development

Four transcript variants encoding the same protein have been identified for this gene

Several transcript variants encoding different isoforms have been found for PPP1R12A

Type I receptors are essential for signaling

providing comprehensive and accurate results

Rb Polyclonal Antibody, 100ul[BT-AP07688] Pathway and Network Analysis It is used as aThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.