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In metabolically healthy men, an infusion of Bay 27-9955, one of the first small-molecule GcgR antagonists, lowered blood glucose in response to a glucagon challenge [53]

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doi: 10.1016/j.physbeh.2006.02.003 35 FiorucciSDistruttiE

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These reports do not prove causation, but they may help identify GLP-1 side effects that are underrepresented in clinical trials