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Tirzepatide as an insulin sensitizer

Regarding the participants with MCI or AD, defined based on a clinical dementia rating (CDR) global score of 0.5 or 1, although the 18-month treatment with exenatide was safe and well-tolerated, it did not significantly affect clinical and cognitive measures, nor did it affect MRI cortical thickness and volume or most biomarkers in the cerebrospinal fluid (CSF), plasma, and plasma neuronal extracellular vesicles (EVs)

Preliminary results indicate that such drugs might not only be effective for obesity and diabetes but also for a number of other diseases including osteoarthritis, Parkinson's disease and a range of conditions caused by a buildup of fat in the liver, known as nonalcoholic steatohepatitis (NASH) (Brandt, Mller, DiMarchi)

For example, poor blood sugar balance can increase cravings and energy crashes

Traditional fiber supplements like Metamucil (psyllium husk) or Citrucel (methylcellulose) expand in the gut to create a bulky gel mass

Back Unger, RH, Eisentraut, AM, Madison et al (1959) 'Glucagon antibodies and their use for immunoassay for glucagon', Experimental Biology and Medicine , 102/3