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Luzindole (LUZ) is a widely used non-selective antagonist of the melatonin receptors MT1 and MT2, enabling us to test whether the effects of exogenous melatonin were receptor-mediated ( Figure 2 Using the same multi-parameter approach applied to the AA model, we evaluated disease outcomes in IL-33 challenged mice in the presence or absence of melatonin and Luzindole

It is a major component of cell membranes, particularly in neurons, and plays a vital role in maintaining cell membrane integrity, neurotransmitter function, and cognitive processes

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In the SS group, one patient experienced a small dural sac rupture that did not require suturing, and there was no postoperative cerebrospinal fluid leakage